Reshaping Hypertension™ with the MobiusHD® System

Now enrolling in the CALM-2 clinical study
for patients with poorly controlled hypertension 

Hypertension impacts 1 billion people worldwide and the clinical consequences are devastating

AMPLIFY

Reshaping of carotid sinus amplifies baroreceptor signaling to the brain

REDUCE

Significant blood pressure reduction demonstrated in multiple clinical studies.

LONG LASTING

Durable safety and efficacy at two-years

NON-SURGICAL

Minimally invasive access using endovascular techniques

Clinical Trials

CALM-FIM  was a prospective, first-in-human, open-label study done at six sites in Europe. The MobiusHD system was studied in patients with an office systolic blood pressure ≥160 mmHg despite taking at least three antihypertensive agents, including a diuretic. 

Results showed a significant decrease in mean ambulatory blood pressure in 73% of patients at 24 hours and blood pressure reduction of 21/12 mmHg at six months, as compared to baseline4.

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